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Immunoregulatory effects of

Dan Luo, Zhengyun Zuo, Hongyan Zhao, Yong Tan, Cheng Xiao

Frontiers of Medicine 2019, Volume 13, Issue 5,   Pages 556-563 doi: 10.1007/s11684-018-0649-5

Abstract: Hook F (TwHF) and its extracts have long been used for the treatment of rheumatoid arthritis, autoimmune

Keywords： <i>Tripterygium wilfordiii> Hook F     immunoregulation     clinical studies    

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Characterization of a Novel Gene, <i>srpAi>, Conferring Resistance to Streptogramin A, Pleuromutilins, and Lincosamides in <i>Streptococcus suisi> Article

Chaoyang Zhang, Lu Liu, Peng Zhang, Jingpo Cui, Xiaoxia Qin, Lichao Ma, Kun Han, Zhanhui Wang, Shaolin Wang, Shuangyang Ding, Zhangqi Shen

Engineering 2022, Volume 9, Issue 2,   Pages 85-94 doi: 10.1016/j.eng.2020.12.015

Abstract: In this study, we identified a new adenosine triphosphate (ATP)-binding cassete (ABC)-F family determinantshares the highest amino acid identity with Vga(E) (36%) and shows canonical characteristics of ABC-F

Keywords： SrpA     Streptococcus suis     Antibiotic resistance     Ribosome     ABC-F family proteins    

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Antifungal and antibacterial functions of medicinal leech recombinant destabilase-lysozyme and its heated-up derivative

F. PISKUNKOVA, I. B. PAVLOVA, L. L. ZAVALOVA, I. P. BASKOVA

Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 2,   Pages 203-209 doi: 10.1007/s11705-012-1277-2

Abstract: Antifungal activity of recombinant medicinal leech destabilase-lysozyme (rec.Dest-Lys) was investigated by using fungi: , and , including yeasts and . Its antibacterial activity was investigated on gram-negative bacteria . These activities were assessed by radial agar diffusion assay, and scanning and transmission electron microscopy. Therefore, destabilase-lysozyme not only is endo-isopeptidase and lysozyme, but also has antifungal and antibacterial activities. Muramidase activity of rec.Dest-Lys disappeared after heat-treating at 90°C for 50 min without the loss of its antimicrobial activity. Furthermore we showed for the first time that the heated-up derivative of rec.Dest-Lys exhibited more potent activities against the above enumerated fungi and gram-negative bacteria than original protein.

Keywords： recombinant destabilase-lysozyme (rec.Dest-Lys)     antimicrobial activity     antifungal activity     medicinal leech     heated-up derivative of rec.Dest-Lys (T-rec.Dest-Lys)    

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Increasing the performance of anaerobic digestion: Pilot scale experimental study for thermal hydrolysis of mixed sludge

S.I. PEREZ-ELVIRA, M. FDZ-POLANCO, F. FDZ-POLANCO,

Frontiers of Environmental Science & Engineering 2010, Volume 4, Issue 2,   Pages 135-141 doi: 10.1007/s11783-010-0024-5

Abstract: The performance of a pilot plant operation combining thermal hydrolysis (170°C, 30 min) and anaerobic digestion (AD) was studied, determining the main properties for samples of fresh mixed sludge, hydrolyzed sludge, and digested sludge, in order to quantify the thermal pretreatment performance (disintegration, solubilisation, and dewaterability) and its impact on the anaerobic digestion performance (biodegradability, volatile solids reduction, and digester rheology) and end product characteristics (dewaterability, sanitation, organic and nitrogen content). The disintegration achieved during the thermal treatment enhances the sludge centrifugation, allowing a 70% higher total solids concentration in the feed to anaerobic digestion. The digestion of this sludge generates 40% more biogas in half the time, due to the higher solids removal compared to a conventional digester. The waste generated can be dewatered by centrifugation to 7% dry solids without polymer addition, and is pathogen free.

Keywords： anaerobic digestion (AD)     biogas     performance     sludge     thermal hydrolysis    

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New insights in the battle between wheat and

Chunlei TANG,Xiaojie WANG,Yulin CHENG,Minjie LIU,Mengxin ZHAO,Jinping WEI,Zhensheng KANG

Frontiers of Agricultural Science and Engineering 2015, Volume 2, Issue 2,   Pages 101-114 doi: 10.15302/J-FASE-2015068

Abstract: Wheat stripe rust caused by f. sp. ( ) poses a great threat to wheat production worldwide.

Keywords： wheat     strip rust     <i>Puccinia striiformisi> f. sp.<i>triticii>     host defense     pathogen virulence     biotrophic fungus    

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Determination of heterozygosity for avirulence/virulence loci through sexual hybridization of

Yuan TIAN,Gangming ZHAN,Xia LU,Jie ZHAO,Lili HUANG,Zhensheng KANG

Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 1,   Pages 48-58 doi: 10.15302/J-FASE-2016114

Abstract: Wheat stripe rust caused by f. sp.An isolate of f. sp.

Keywords： <i>Puccinia striiformisi> f. sp. <i>triticii>     selfing     heterozygosity     virulence inheritance    

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Bacteria-mediated tumor-targeted delivery of tumstatin (54-132) significantly suppresses tumor growth in mouse model by inhibiting angiogenesis and promoting apoptosis

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 873-882 doi: 10.1007/s11684-022-0925-2

Abstract: VNP20009, an attenuated <i>Salmonella typhimuriumi> strain, preferentially accumulates in the hypoxicIn this study, a novel <i>Salmonellai>-mediated targeted expression system of tumstatin (VNP-Tum5)Treatment with VNP-Tum5 effectively suppressed tumor growth and prolonged survival in the mouse model of B16F10exhibited a higher efficacy in inhibiting the proliferation and inducing the necrosis and apoptosis of B16F10cells <i>in vitroi> and <i>in vivoi> compared with VNP (control).

Keywords： <i>Salmonellai> VNP20009     tumstatin     B16F10     melanoma     apoptosis     angiogenesis    

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Pressure drop analysis on the positive half-cell of a cerium redox flow battery using computational fluid dynamics: Mathematical and modelling aspects of porous media

Fernando F. Rivera, Berenice Miranda-Alcántara, Germán Orozco, Carlos Ponce de León, Luis F. Arenas

Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 2,   Pages 399-409 doi: 10.1007/s11705-020-1934-9

Abstract: Description of electrolyte fluid dynamics in the electrode compartments by mathematical models can be a powerful tool in the development of redox flow batteries (RFBs) and other electrochemical reactors. In order to determine their predictive capability, turbulent Reynolds-averaged Navier-Stokes (RANS) and free flow plus porous media (Brinkman) models were applied to compute local fluid velocities taking place in a rectangular channel electrochemical flow cell used as the positive half-cell of a cerium-based RFB for laboratory studies. Two different platinized titanium electrodes were considered, a plate plus a turbulence promoter and an expanded metal mesh. Calculated pressure drop was validated against experimental data obtained with typical cerium electrolytes. It was found that the pressure drop values were better described by the RANS approach, whereas the validity of Brinkman equations was strongly dependent on porosity and permeability values of the porous media.

Keywords： CFD simulation     porous media     porous electrode     pressure drop     redox flow battery    

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Development of soft kernel durum wheat

Craig F. MORRIS

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 3,   Pages 273-278 doi: 10.15302/J-FASE-2019259

Abstract:

Kernel texture (grain hardness) is a fundamental and determining factor related to wheat ( spp.) milling, baking and flour utilization. There are three kernel texture classes in wheat: soft and hard hexaploid ( ), and very hard durum ( subsp. ). The genetic basis for these three classes lies with the Puroindoline genes. Phenotypically, the easiest means of quantifying kernel texture is with the Single Kernel Characterization System (SKCS), although other means are valid and can provide fundamental material properties. Typical SKCS values for soft wheat would be around 25 and for durum wheat≥80. Soft kernel durum wheat was created via homeologous recombination using the mutation, which facilitated the transfer of ca. 28 Mbp of 5DS that replaced ca. 21 Mbp of 5BS. The 5DS translocation contained a complete and intact locus and both puroindoline genes. Expression of the puroindoline genes in durum grain resulted in kernel texture and flour milling characteristics nearly identical to that of soft wheat, with high yields of break and straight-grade flours, which had small particle size and low starch damage. Dough water absorption was markedly reduced compared to durum flour and semolina. Dough was essentially unchanged and reflected the inherent gluten properties of the durum background. Pasta quality was essentially equal-to-or-better than pasta made from semolina. Agronomically, soft durum germplasm showed good potential with moderate grain yield and resistance to a number of fungal pathogens and insects. Future breeding efforts will no doubt further improve the quality and competitiveness of soft durum cultivars.

Keywords： soft durum wheat     grain hardness     puroindolines     milling     baking     pasta     noodles    

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Biocompatibility Pathways in Tissue-Engineering Templates Perspective

David F. Williams

Engineering 2018, Volume 4, Issue 2,   Pages 286-290 doi: 10.1016/j.eng.2018.03.007

Abstract:

Tissue engineering, which involves the creation of new tissue by the deliberate and controlled stimulation of selected target cells through a systematic combination of molecular and mechanical signals, usually involves the assistance of biomaterials-based structures to deliver these signals and to give shape to the resulting tissue mass. The specifications for these structures, which used to be described as scaffolds but are now more correctly termed templates, have rarely been defined, mainly because this is difficult to do. Primarily, however, these specifications must relate to the need to develop the right microenvironment for the cells to create new tissue and to the need for the interactions between the cells and the template material to be consistent with the demands of the new viable tissues. These features are encompassed by the phenomena that are collectively called biocompatibility. However, the theories and putative mechanisms of conventional biocompatibility (mostly conceived through experiences with implantable medical devices) are inadequate to describe phenomena in tissue-engineering processes. The present author has recently redefined biocompatibility in terms of specific materials- and biology-based pathways; this opinion paper places tissue-engineering biocompatibility mechanisms in the context of these pathways.

Keywords： Biomaterials     Scaffolds     Mechanotransduction     Inflammation     Topography    

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Resistance of large deformation of the Wushaoling Tunnel F7 soft fault

ZHAO Xufeng, CHEN Haiming, WANG Chunmiao

Frontiers of Structural and Civil Engineering 2007, Volume 1, Issue 1,   Pages 123-127 doi: 10.1007/s11709-007-0013-3

Abstract: In this article, the mechanical characteristics of the squeeze of the F7 fault of the Wushaoling Tunnel

Keywords： F7     deformation     appropriate     construction     mechanical    

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Special issue on future network: software-defined networking Editorial

Tao HUANG,F. Richard YU,Yun-jie LIU

Frontiers of Information Technology & Electronic Engineering 2016, Volume 17, Issue 7,   Pages 603-605 doi: 10.1631/FITEE.SDN2016

Abstract: 无

Keywords： 无    

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Nanocrystal technology for drug formulation and delivery

Tzu-Lan CHANG, Honglei ZHAN, Danni LIANG, Jun F. LIANG

Frontiers of Chemical Science and Engineering 2015, Volume 9, Issue 1,   Pages 1-14 doi: 10.1007/s11705-015-1509-3

Abstract: administration routes allow drug nanocrystals to be a novel drug delivery system for specific diseases (i.e

Keywords： drug nanocrystal     nanotechnology     formulation     bioavailability     stabilizers     drug delivery    

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Decomposing drivers of transportation energy consumption and carbon dioxide emissions for the Philippines: the case of developing countries

Neil Stephen LOPEZ, Anthony S.F. CHIU, Jose Bienvenido Manuel BIONA

Frontiers in Energy 2018, Volume 12, Issue 3,   Pages 389-399 doi: 10.1007/s11708-018-0578-7

Abstract:

Global CO2 emissions increased by 57.9% from 1990 to 2014, of which 21% is known to be from the transportation sector. In line with policy development, driving forces to energy consumption and emissions may be determined using decomposition analysis techniques. However, the detail of information required to perform such studies for the transportation sector in developing countries can be challenging. An attempt was made in this study to formulate a decomposition analysis framework considering data availability and limitation in developing countries. Furthermore, a suggestion of adjusting transport activity data using average oil price was proposed. An illustrative case study in the Philippines revealed that the most significant driver was transport activity, followed by energy intensity, and then population growth, which was both similar and contrary to all previous studies performed in developed and rapidly urbanizing countries, which pointed out to transport activity as the primary contributing force. For the Philippines, transport activity was an inhibiting force, whereas energy intensity was the primary contributing factor. The difference could be explained by the differences in mode shares and quality of life between countries. Looking at private vehicle ownership data, it is observed that growth rates are higher in the rural, than in the urban centers. Deriving from the findings, developing a comprehensive public transport plan is recommend for future growth areas, expansion and modernization of public transport services in the city, and strategic deployment of transport policies.

Keywords： transportation     LMDI     decomposition     developing country     emissions    

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Comments on the special issue on Agri-product Quality and Safety

Charles F. SHOEMAKER

Frontiers of Agricultural Science and Engineering 2018, Volume 5, Issue 3,   Pages 294-294 doi: 10.15302/J-FASE-2018237

Abstract:

Keywords： valign=     top     class=     J_zhaiyao    

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Title Author Date Type Operation

Immunoregulatory effects of

Dan Luo, Zhengyun Zuo, Hongyan Zhao, Yong Tan, Cheng Xiao

Journal Article

Characterization of a Novel Gene, <i>srpAi>, Conferring Resistance to Streptogramin A, Pleuromutilins, and Lincosamides in <i>Streptococcus suisi>

Chaoyang Zhang, Lu Liu, Peng Zhang, Jingpo Cui, Xiaoxia Qin, Lichao Ma, Kun Han, Zhanhui Wang, Shaolin Wang, Shuangyang Ding, Zhangqi Shen

Journal Article

Antifungal and antibacterial functions of medicinal leech recombinant destabilase-lysozyme and its heated-up derivative

F. PISKUNKOVA, I. B. PAVLOVA, L. L. ZAVALOVA, I. P. BASKOVA

Journal Article

Increasing the performance of anaerobic digestion: Pilot scale experimental study for thermal hydrolysis of mixed sludge

S.I. PEREZ-ELVIRA, M. FDZ-POLANCO, F. FDZ-POLANCO,

Journal Article

New insights in the battle between wheat and

Chunlei TANG,Xiaojie WANG,Yulin CHENG,Minjie LIU,Mengxin ZHAO,Jinping WEI,Zhensheng KANG

Journal Article

Determination of heterozygosity for avirulence/virulence loci through sexual hybridization of

Yuan TIAN,Gangming ZHAN,Xia LU,Jie ZHAO,Lili HUANG,Zhensheng KANG

Journal Article

Bacteria-mediated tumor-targeted delivery of tumstatin (54-132) significantly suppresses tumor growth in mouse model by inhibiting angiogenesis and promoting apoptosis

Journal Article

Pressure drop analysis on the positive half-cell of a cerium redox flow battery using computational fluid dynamics: Mathematical and modelling aspects of porous media

Fernando F. Rivera, Berenice Miranda-Alcántara, Germán Orozco, Carlos Ponce de León, Luis F. Arenas

Journal Article

Development of soft kernel durum wheat

Craig F. MORRIS

Journal Article

Biocompatibility Pathways in Tissue-Engineering Templates

David F. Williams

Journal Article

Resistance of large deformation of the Wushaoling Tunnel F7 soft fault

ZHAO Xufeng, CHEN Haiming, WANG Chunmiao

Journal Article

Special issue on future network: software-defined networking

Tao HUANG,F. Richard YU,Yun-jie LIU

Journal Article

Nanocrystal technology for drug formulation and delivery

Tzu-Lan CHANG, Honglei ZHAN, Danni LIANG, Jun F. LIANG

Journal Article

Decomposing drivers of transportation energy consumption and carbon dioxide emissions for the Philippines: the case of developing countries

Neil Stephen LOPEZ, Anthony S.F. CHIU, Jose Bienvenido Manuel BIONA

Journal Article

Comments on the special issue on Agri-product Quality and Safety

Charles F. SHOEMAKER

Journal Article